CHOLINESTERASE INHIBITORY ACTIVITY OF CERTAIN PLANT EXTRACTS

Cholinesterase is a serine hydrolase which catalyzes the hydrolysis of neurotransmitter acetylcholine into choline and acetic acid. According to cholinergic neurotransmission, cholinesterase inhibition would increase the levels of acetylcholine in the brain, thus improving cholinergic synapses in Alzheimer's disease. In the traditional medicine, numerous plants have been used to treat cognitive disorders. Natural products play an essential role in prevention and therapy of various neurodegenerative diseases and neuronal dysfunctions. The present book will focus on the in silico and in vitro cholinesterase inhibition of Moringa oleifera and Musa paradisiaca plant extracts. Designing such a book in the field of neuropharmacology is a challenging task, especially if it is to be concise and comprehensive in scope.This book forms a valuable addition to the existing body of knowledge and is especially intended for neuropharmacology researchers and post graduate students of Pharmacy students.