Chemistry of 1,3-oxathiolan-5-ones

This book highlighted the methods used for synthesis of 1,3-oxathiolan-5-one derivatives, besides, covered many reports of the applications of multicomponent domino reactions (MDRs) in the synthesis of novel stereocontrolled mercapto-heterocycles. In addition, it reported theoretically studies for the all of the new synthesized compounds. In this context, we reported herein peculiar reaction behavior of 2-methyl-2-phenyl-1,3-oxathiolan-5-one which acts as acyl transfer agent towards various reagents through acyl transfer. The methods of the synthesis and synthetic mechanisms of the aforementioned reactions were well presented and the structures of these compounds were assessed by analytical and spectral data.