Bridelia Ferruginea, Diaminazene Aceturate Effect on Trypanosomosis

Over 66 million people in sub-Saharan Africa suffer from sleeping sickness caused by trypanosomes. If not treated, the resultant effect is death. Trypanosomosis in livestock causes drastic weight loss, decrease in milk yield, decrease in carcass quality and inability to work due to poor feed conversion efficiency. It has been reported that trypanosomosis reduces reproductive function in male animals. It causes decrease in libido, delayed maturity, degeneration of the testicles leading to production of poor quality spermatozoa in male animals. Bridelia ferruginea and Diaminazene aceturate have been recorded to have purgative effect, reduce microbial proliferation, combat inflammation and trypanocidal respectively. Therefore, a combination therapy of the two drugs will be effective in ameliorating the reproductive disorders induced by trypanosomes for livestock farmers in the sub-Saharan Africa.