Bone Biomarkers in Periodontal Diseases

A goal of periodontal diagnostic procedures is to provide useful information to the clinician regarding the present periodontal disease type, location, and severity. These findings serve as a basis for treatment planning and provide essential data during periodontal maintenance and disease-monitoring phases of treatment. Advances in oral and periodontal disease diagnostic research are moving toward methods whereby periodontal risk can be identified and quantified by objective measures such as biomarkers. Biomarkers are the biological, biochemical, anthropometric, physiological, which are objectively measurable, capable of identifying physiological or pathological processes, or a pharmacological response or a therapeutic intervention. A single biomarker will not able to predict periodontal disease activity and severity. So combinations of biomarkers are used to predict the disease activity including bone remodelling biomarkers.