Biocompatibility study of Hydroxyapatite

Among the bioactive ceramics Hydroxyapatite (HA) is an inorganic, insoluble calcium phosphate salt and owing to its biocompatibility and osteoconductive properties it is a desirable implant material. Hydroxyapatite (HA) is one of the most stable crystal structures of the calcium phosphates. Hydroxyapatite (HA) is the principal bioactive The aim of this work is to synthesize phase pure hydroxyapatite by the wet precipitation method which is the simplest method for the synthesis of hydroxyl apatite. To evaluate the phase purity of hydroxyapatite and to know the effect of stirring speed and time on the phase purity. To study the morphology of HA particles and its size variation with stirring time. To determine how stirring time effect of the crystallite size and crystallinity degree. To evaluate the phase purity of hydroxyapatite and to know the effect of refluxing time on the phase purity. To study the morphology of HA particles and its size variation with refluxing time. To examine how refluxing time effect of the crystallite size and crystallinity degree. In vitro assessment of bioactivity of synthesized hydroxyapatite powder in simulated body fluid.