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Beschreibung
Ataxia-telangiectasia or A-T is a fatal progressive
neurological disease of children. The symptoms indicate
disruptions in the development of such diverse body parts as
cerebellum, thymus and chromosomes. The patients are unduly
sensitive to ionizing radiation, immunodeficient, and a
third of them develops cancer. All of this stems from
defects of a single gene.
Provided here is an up-to-date review of all important work
in thefield. A wide spectrum of topics is covered, namely
genetics, chromosome 11 mapping, radiobiology,
complementation, heterozygote identification, clinical
variants, biochemistry, and treatment of A-T.
Details
| Verlag | Springer Berlin |
| Ersterscheinung | 23. Juni 2012 |
| Maße | 23.5 cm x 15.5 cm |
| Gewicht | 482 Gramm |
| Format | Softcover |
| ISBN-13 | 9783642782800 |
| Seiten | 283 |
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