Antimicrobial Activities of Streptomyces species in Akure Metropolis

In this book, antimicrobial activities of Streptomyces of three plantation soils in Akure metropolis against some pathogenic bacteria was carried out.Purification of the Streptomyces filtrates was done by column chromatography using chloroform and methanol in the ratio of 2:1 (v/v). The antibacterial and antifungal activities of crude and partially purified metabolites were evaluated against typed and clinical cultures (human and plant) of some pathogenic bacteria. For control experiment, antibiotic sensitivity pattern of the pathogenic organisms was determined by using sensitivity disc. Streptomyces collinus ORFUTA was the most effective in inhibition of pathogenic bacteria for both crude and purified metabolite.while the commercial drugs and fungicides used was more effective than the metabolites produced by Streptomyces species.Streptomyces collinus from orange plantation soil from Federal university of Technology Akure can be exploited in antibiotics production to treat staphylococcal infection.