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The present study was undertaken to investigate the Antifungal activity of a locally found and ethnobotanically important plant Solanum xanthocarpum. Schard and vendle. (kantakari) .The crude extracts of powdered plant material were obtained in various polar and nonpolar solvents viz: petroleum ether, chloroform, methanol and distilled water. Well defined zones of inhibition were recorded indicating that solanum xanthocarpum was potent against pathogenic fungus i.e. A. niger, A. flavus, A. candidus, A.parasiticus. The chloroform extract of whole plant showed significant inhibitory zone against Aspergillus niger . Comparatively the other extracts of whole plant were not more active against the other fungal strains. Standard antimicrobial discs: Fuconazole and Ketoconazole were used to test their antifungal potential and the discs showed remarkable zones of inhibition against the fungal strains which are at some extent comparable with the plant extract values.