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Anticonvulsant activity of pentazocine and its probable mechanism

Anticonvulsant activity of pentazocine and its probable mechanism

von Praveen Panchaksharimath, Shailender Singh und Siddappa Devaru
Softcover - 9783848493692
49,00 €
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Beschreibung

Pentazocine, which is known to act as an agonist at kappa opioid receptors and a weak antagonist or a partial agonist at mu receptors has shown significant anticonvulsant activity in MES test and abolition of this anticonvulsant activity by high dose but not by low dose of Naloxone. The present study was designed to compare the anticonvulsant effect of Pentazocine with standard Sodium Valproate in albino rats. An attempt was also made to determine the possible opioid receptor mechanism involved.

An Experimental Pharmacological Study

Details

Verlag LAP LAMBERT Academic Publishing
Ersterscheinung 29. März 2012
Maße 22 cm x 15 cm x 0.6 cm
Gewicht 137 Gramm
Format Softcover
ISBN-13 9783848493692
Seiten 80