Actual problems of diagnosis and treatment of thoracoabdominal injuries

The problem of injury in many countries is very acute. Trauma kills more people under the age of 45 than any other cause. Trauma is now the second leading cause of death. By 2020, worldwide, the number of deaths from injuries will increase from 5.8 to 8.4 million cases per year. Thoracoabdominal trauma is a particular difficulty in diagnosis and treatment. The main pathogenetic factors of any injury, such as acute blood loss, hypoxia, immune distress syndrome, break down physiological adaptive mechanisms, triggering a traumatic illness. Timely adequate correction of acute blood loss and relief of the phenomenon of hemodilutionary coagulopathy lead to the need to use donor components. However, the results of massive transfusion protocols and coagulation factor correction are mixed. The thresholds for transfusion of blood components, depending on morbid pathology, have not been definitively determined.