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A Network-Based Approach to Cell Metabolism

von Oriol Güell
Hardcover - 9783319639994
106,99 €
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Beschreibung

This thesis uses a systems-level approach to study the cellular metabolism, unveiling new mechanisms and responses that were impossible to reach with traditional reductionists procedures.

The results reported here have a potential application in areas like metabolic engineering and disease treatment. They could also be used in determining the accuracy of the gene essentiality of new genome-scale reconstructions.

Different methods and techniques, within the contexts of Systems Biology and the field known as Complex Networks Analysis have been applied in this work to show different features of the robustness of metabolic networks. The specific issues addressed here range from pure topological aspec

ts of the networks themselves to the balance of biochemical fluxes.

 

From Structure to Flux Balances

From Structure to Flux Balances

Details

Verlag Springer International Publishing
Ersterscheinung 24. August 2017
Maße 23.5 cm x 15.5 cm
Gewicht 3849 Gramm
Format Hardcover
ISBN-13 9783319639994
Auflage 1st ed. 2017
Seiten 151