Wurster Process: A Technical Approach

Fluid ¿ Bed Processors that have been developed offer a unique opportunity to develop and produce coated controlled- release products. However, various process parameters, such as those discussed in this chapter, easily can alter performance of the product and hence should be examined thoroughly during sale¿up phase.The purpose of this chapter is to provide a brief guide for scaling up a wurster process from scale up lab to production scale. The Theoretical Scale Up section describes how to theoretically calculate the starting operating parameters when scaling up a process. The process parameters in the Wurster process are controllable precisely, which ensures easier optimization and reproducibility of the product quality.