Synthesis, Characterization & Antibacterial activities

The title Zn (II) complex was synthesized by reacting the compound Bis-[(E)-3{2-(1-4-chlorophenyl) ethylidiene]hydrazinyl}-N-(4-methylphenyl)-3-oxo propanamide with Zn (II) chloride dehydrate in alkaline dimethylsulphoxide and ethanol solution under reflexing condition for 8 hours. The resultant colorless compound was filtered and recrystallized from the mixture of dimethylsulphoxide and ethanol. The hydrazone Schiff base and its Zn (II) complex were characterized by using UV-Vis spectroscopy and XRD, TEM and SEM analysis. The antibacterial activities of hydrazone Schiff base and its Zn complex were examined using disc diffusion method. The spectra result showed that the hydrazone Schiff base ligand undergoes keto-enoltautomerism forming a bidentated ligand (N, N) towards Zn+2 (II) ions. It is very interesting that on sides of the two hydrazone Schiff base ligands which coordinate to the Zn+2 ions, an additional two thiosemicarbazine moiety were also coordinated with Zn+2 ions in the crystalline powder, resulting in a hexa coordinated distorted octahedral Zn (II) complex.