Solvents: Microscopic Properties - Empirical Parameters. Part 2

This book groups pure solvents (capable of forming complexes via hydrogen bonding with each other) and their binary mixtures, on the basis of the similarity of their microscopic molecular properties (dipolarity, acidity, basicity) characterized by Solvatochromic Parameters. The grouping is carried out by means of a Multivariate Statistical Treatment, taking as variables the Parameters of two Solvatochromic Comparison Methods, Kamlet, Abboud and Taft's (pi*, alpha and beta) and Catalán's (SPP, SA and SB). The study pays special attention to the microscopic features common to the solvents included in each group, which describe their relevant solvation properties. It also offers a comparison of the results obtained with both methods, which yields an important agreement and a satisfactory correlation with kinetic data of Nucleophilic Aromatic Nucleophilic Substitution reactions carried out in the same solvent systems in which the parameters were determined. This offers a valuable tool for the prediction of reaction rates carried out in these media and the possibility of extending them to other processes in solution.