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Possible mechanisms of methylmercury neurotoxicity

Possible mechanisms of methylmercury neurotoxicity

von Ezzat Awad
Softcover - 9783846585504
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Beschreibung

Different studies reported that glutathione (GSH) play a major role in modulating methylmercury (MeHg) neurotoxicity. Glutathione synthetase deficiency (GSD) and 5- Oxoprolinase deficiencies are two inborn errors of GSH metabolism; which were associated with physiological and pathological features resembling patients with Minamata disease (MD). The present study aimed to investigate whether there are similarities between the metabolic effects of MeHg and 5-oxoprolinase inhibitor (ICA) on both C6 Glial cells and PC12 neurons.

Correlation between The Metabolic Effects of Methylmercury and 5-Oxoprolinease inhibitor on both C6 Glial cells and PC12

Details

Verlag LAP LAMBERT Academic Publishing
Ersterscheinung 15. Juni 2012
Maße 22 cm x 15 cm x 0.7 cm
Gewicht 173 Gramm
Format Softcover
ISBN-13 9783846585504
Seiten 104

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