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Beschreibung
A comprehensive modelling methodology for analysis of the kinetics of non-native protein aggregation based on general population balance model within the Extended Lumry-Eyring framework is presented. The population balance model is formulated in terms of key parameters, describing relative importance of (un)folding and aggregation kinetics of a protein in diffusion-driven conditions. Both the analytical and numerical solution provide a detailed insight on the intrinsic aggregation kinetics via time-dependent evolution of a variety of experimentally measurable quantities.
Kinetics of protein aggregation
Details
| Verlag | LAP LAMBERT Academic Publishing |
| Ersterscheinung | 21. August 2012 |
| Maße | 22 cm x 15 cm x 0.8 cm |
| Gewicht | 179 Gramm |
| Format | Softcover |
| ISBN-13 | 9783659212031 |
| Seiten | 108 |
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