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Beschreibung
Single cell analysis has typically been difficult and challenging to perform in such a way that meaningful statistical information can be extracted. This thesis documents the development of a microchip or lab-on-a-chip platform to perform single cell electrophoresis in parallel separation channels. It describes the use of optical tweezers to select a cell and transport it to a desired separation channel. It also describes the use of electromechanical shearing to lyse a cell. These two techniques are combined with laser-micromachined separation channels to perform simple electrohoresis on the fluorescently labeled cellular contents.
Details
| Verlag | LAP LAMBERT Academic Publishing |
| Ersterscheinung | 30. Mai 2010 |
| Maße | 22 cm x 15 cm x 0.9 cm |
| Gewicht | 227 Gramm |
| Format | Softcover |
| ISBN-13 | 9783838304489 |
| Seiten | 140 |
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