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Model Systems in Aging

Hardcover - 9783540024903
213,99 €
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Softcover - 9783642056987
213,99 €

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Weitere Formate

Softcover - 9783642056987
213,99 €

Beschreibung

Aging is the progressive decline in biological functions over time. This decline targets macromolecules, cells, tissues and, as a consequence, whole organisms. Despite considerable progress in the development of testable hypothesis concerning aging in an evolutionary context, a unifying theory of the molecular/physiological mechanistic causes of aging has not been reached. In fact, is it not clear to what extent aging is a programmed or stochastic process.

This book takes the reader from unicellular bacterial deterioration via senescence in fungi and worms to aging in rodents and humans, allowing a comparative view on similarities and differences in different genetic model systems. The different model systems are scrutinized in the light of contemporary aging hypothesis, such as the free radical and genomic instability theories.

Details

Verlag Springer Berlin
Ersterscheinung 22. September 2003
Maße 22.9 cm x 15.2 cm
Gewicht 641 Gramm
Format Hardcover
ISBN-13 9783540024903
Auflage 2004
Seiten 301

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