Mitochondriopathy and Sexuality

The Neanderthal brain structure results in female dominance and matriarchal social patterns. It was considered plausible that Neanderthal genomics and metabolonomics could also contribute to androgynous behaviour. It has been demonstrated that Neanderthal phenotype is due to symbiosis by actinidic archaea using cholesterol as an energy substrate. Cholesterol is also converted to steroidogenic estrogens and testosterone. The increasing growth of actinidic archaea converts the body metabolites the cholesterol which is subsequently oxidized and depleted. Cholesterol is also converted by actinidic archaea to endogenous digoxin which helps to integrate the neuro-immuno-endocrine system. Digoxin produces sodium-potassium ATPase inhibition and increased in intracellular calcium inducing nitric oxide synthase and heme oxygenase generating gasotransmitters nitric oxide and carbon monoxide important in smooth muscle contraction and autonomic function.