Microbiology and Aging

Chapter7highlightsthechangesthatoccurintheoral micro?ora and host defences with advanced age with Chap. 8 reviewing the in?uenceofthegutmicrobiotawithageing. Chapter8focusesonthegutandits associatedimmunity. Theremainingfourchaptersofthebookconsiderclostridium andtheageinggut,Helicobacterpyloriandthehygienehypothesisandthebene?ts of probiotics. The microbiology theory of autism in children is reviewed in vii viii Preface Chap. 13. The?nalchapterofthebookexamineshowthebene?cialmicrobiology ofthehostleadstohumandecomposition. Thisbookencompassesacollectionofreviewsthathighlightthesigni?canceof andthecrucialrolethatmicroorganismsplayinthehumanlifecycle. Flintshire,UK StevenL. Percival Contents 1 AgeingTheories,DiseasesandMicroorganisms. . . . . . . . . . . . . . . . . . . . . . . . . 1 StevenL. Percival 2 IndigenousMicrobiotaandAssociationwiththeHost. . . . . . . . . . . . . . . . . 15 JohnG. ThomasandStevenL. Percival 3 InfectionsintheElderly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 KnutOhlsen,SvitlanaKozytska,andUdoLorenz 4 SkinAgingandMicrobiology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 LeslieBaumann,EdmundWeisberg,andStevenL. Percival 5 LungInfectionsandAging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 SameerK. MathurandKeithC. Meyer 6 In?uenzaintheElderly. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 CaterinaHatzifotiandAndrewWilliamHeath 7 ChangesinOralMicro?oraandHostDefences withAdvancedAge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131 RimondiaS. Percival 8 In?uenceoftheGutMicrobiotawithAgeing. . . . . . . . . . . . . . . . . . . . . . . . . 153 EileenMurphy,CarolineMurphy,andLiamO¿Mahony 9 AGutReaction:AgingAffectsGut-AssociatedImmunity . . . . . . . . . . 175 JosephF. Albri