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Dendritic Cell-based Vaccine Strategies in MTB Infection

Dendritic Cell-based Vaccine Strategies in MTB Infection

von Gesham Magombedze, Nothabo Dube und Winston Garira
Softcover - 9783845429472
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Beschreibung

Dendritic cells (DCs) are known to play a pivotal role in linking the innate and adaptiveimmune mechanisms. We study the effects of a Dendritic cell based vaccine in the fightagainst Mycobacterium tuberculosis. First a model without immune response is considered, then a model with T and CTL mechanisms, then a model with T,CTL and Dendritic cells and finally a model with a dendritic cell-based vaccine. From our model analysis, we conclude that the introduction of a cell-based vaccine can go a long way towards the effective control of the Mtb infection.

Mathematical Modeling of Dendritic Cell-Based Vaccination Strategies in Mycobacterium Tuberculosis Infection

Details

Verlag LAP LAMBERT Academic Publishing
Ersterscheinung 18. August 2011
Maße 22 cm x 15 cm x 0.6 cm
Gewicht 161 Gramm
Format Softcover
ISBN-13 9783845429472
Seiten 96

Schlagwörter

Naturwissenschaften - allgemein