Clinicopathological Patterns of Osteosarcoma Patients

Osteosarcoma is a high-grade malignant bone tumor capable of forming a lace-like bony matrix. It has a bimodal incidence distribution, with the highest peak in the second decade and a lesser peak in late adult life. Osteosarcoma afflicted mainly teenagers (median age = 17 years). Fifty eight percent of patients were males and 42% were females. Twenty two percent of patients live in Khartoum state, while 56% live in district states. Living in Khartoum conferred early detection and shorter duration of symptoms. The mean duration of symptom was 7 months. Pain and swelling comprised the cardinal presenting features. Four patients presented with pathological fractures. Metaphysis of long bones was the forerunner hotspot comprising 74%, of whom, sixty percent were around the knee joint. Sixty four percent of cases orig- inated in the medulla and 12% from the cortex. Conventional osteosarcoma represents 72% of cases with predominance of the osteoblastic type. Eighty percent of cases were assigned as high grade.