{"product_id":"venlafaxine-vs-fluvoxamine-in-ocd-von-lavina-prashar-und-ravi-paul","title":"Venlafaxine vs Fluvoxamine in OCD","description":"\u003cp\u003eObjective: To compare the efficacy and tolerability of fluvoxamine and venlafaxine in patients with obsessive-compulsive disorder. Materials and Methods: Forty newly diagnosed patients of OCD (DSM-IV-TR criteria) were randomized to receive either Fluvoxamine (F) or Venlafaxine (V). The dose of fluvoxamine was titrated upwards from 50 to 300 mg\/day and of venlafaxine from 75 to 375mg\/day to achieve optimal clinical effects. The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) was used as an index of efficacy ( \u0026lt; 25% reduction in score). Drug responders were defined as score of 2 (much improved) or 1 (very much improved) on Clinical Global Impression Scale of improvement. Results:Y-BOCS score improvement occurred earlier and was higher in F-group (week 4 onwards) as compared to V-group (p\u0026gt;0.05). Eleven patients obtained a score of ¿2¿ or ¿1¿ in F-group versus four in V-group. ADR profile was similar in both groups except for loss of libido which was significantly higher in F-group and headache in V-group. Conclusion: Though venlafaxine has a dual action but fluvoxamine with more selective action on the serotoninergic system shows better better symptomatic relief in OCD\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783847341697\"\u003e\u003ch3\u003eA Comparative, Randomized, Open Labelled, Parallel Study for Efficacy and Tolerability of Fluvoxamine and Venlafaxine\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783847341697","offer_id":39493645271133,"sku":"9783847341697","price":59.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/47fea0f1-5bed-4222-9b4f-d59f97d6cfe6.jpg?v=1758346293","url":"https:\/\/shop.autorenwelt.de\/products\/venlafaxine-vs-fluvoxamine-in-ocd-von-lavina-prashar-und-ravi-paul","provider":"Autorenwelt Shop","version":"1.0","type":"link"}