{"product_id":"tumor-budding-in-primary-pancreatic-adenocarcinoma-von-sarra-ben-rejeb-und-jasser-yaacoubi","title":"Tumor budding in primary pancreatic adenocarcinoma","description":"\u003cp\u003eTumor budding (BT) is an emerging prognostic factor in several cancers, including pancreatic cancer. Our bi-centric study (2008-2022) aimed to evaluate BT by morphological method and with QUPATH software, and to analyze its impact on overall and event-free survival. We included 25 cases of pancreatic adenocarcinoma, with a mean age of 62 years and a male predominance (72%). BT was detected in 100% of cases morphologically and 80% by QUPATH. A high BT (BUD2\/BUD3) was found in 56% of cases morphologically and 48% by QUPATH, with no significant difference between methods (p=0.589). A high BT was associated with advanced age (p=0.03) and negatively influenced overall survival (p=0.038). This study suggests that BT is a key prognostic factor and that QUPATH could become an accessible tool for standardizing its assessment in pathology.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786208634636\"\u003e\u003ch3\u003eAnalysis on digital images\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9786208634636","offer_id":54103133094213,"sku":"9786208634636","price":60.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/a1927018-3c98-48eb-be75-cf10cdb84b17.jpg?v=1770364512","url":"https:\/\/shop.autorenwelt.de\/products\/tumor-budding-in-primary-pancreatic-adenocarcinoma-von-sarra-ben-rejeb-und-jasser-yaacoubi","provider":"Autorenwelt Shop","version":"1.0","type":"link"}