{"product_id":"three-models-of-huntingtons-disease-von-aysha-s-raza","title":"Three Models of Huntington's Disease","description":"\u003cp\u003eHuntington''s disease (HD) is a purely genetic neurodegenerative  disorder affecting approximately 1 in 10,000 people.  It is most  commonly associated with excessive involuntary movement, or chorea,  combined with varying degrees of other motor, psychiatric and  cognitive disturbances.  Identification of the mutation in the HD gene  prompted the generation of several transgenic mouse models.  HD is  but one of a family of at least 9 triplet repeat disorders, all of which  exhibit protein aggregation by a similar mechanism. The  understanding of one disease is therefore of importance to the  understanding of them all.  This work aims to be a comprehensive  comparative study of three very different mouse models of HD  elucidating the pathological changes that precede and accompany the  disease process.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838328843\"\u003e\u003ch3\u003eThe Neuropathological Investigations of Transgenic Murine Models of Disease\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838328843","offer_id":39469144146013,"sku":"9783838328843","price":79.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/5032320f-2931-495f-9f2a-e1750f6506fb.jpg?v=1738393921","url":"https:\/\/shop.autorenwelt.de\/products\/three-models-of-huntingtons-disease-von-aysha-s-raza","provider":"Autorenwelt Shop","version":"1.0","type":"link"}