{"product_id":"the-tales-of-polya-tails-von-victoria-portnoy","title":"The tales of poly(A) tails","description":"\u003cp\u003ePolyadenylation is a process common to almost all organisms. In eukaryotes, stable poly(A) tails are added to the 3'' end of most mRNAs, which is  important for mRNA stability and translation initiation. In contrast, polyadenylation can stimulate RNA degradation; a phenomenon witnessed in prokaryotes, organelles and nucleus- encoded RNA. In general,  this decay process consists of sequential events  including endonucleolytic cleavage, the addition of  degradation stimulated poly(A) sequence to the proximal cleavage products, and rapid exonucleolytic degradation. The results of this work brought us to suggest a  possible scenario for the evolution of polyadenylation.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783843351492\"\u003e\u003ch3\u003eThe interplay between polyadenylation and degradation of RNA in the three Domains of Life\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783843351492","offer_id":39497018900573,"sku":"9783843351492","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/a5f53aac-f1b2-4cc5-b8a8-55565136ed7f.jpg?v=1757743000","url":"https:\/\/shop.autorenwelt.de\/products\/the-tales-of-polya-tails-von-victoria-portnoy","provider":"Autorenwelt Shop","version":"1.0","type":"link"}