{"product_id":"the-chaperone-action-of-small-heat-shock-protein-alpha-crystallin-von-arezou-ghahghaei","title":"The Chaperone action of small heat shock protein, alpha-crystallin","description":"\u003cp\u003e¿-Crystallin is the principal lens protein. It is a  member of the small heat shock protein family  (sHsp) and acts as a molecular chaperone by  stabilizing proteins under stress conditions  through the formation of a soluble sHsp target  protein complex to prevent their aggregation.  Macromolecular crowding is ubiquitous in all types  of cells and describes the normal conditions inside  a cell. The concentration of macromolecules inside  a cell is very high (up to 300 mg\/mL). Thus, there  is a major difference between in vivo and in vitro  conditions such as those used in most studies of  protein behaviour and properties.   In vitro, much work has been published on the  interactions of ¿-crystallin with target proteins  in dilute solutions. In this book in order to  better understand the chaperone activity of ¿- crystallin under conditions more closely resembling  the intracellular environment, its interaction with  a range of destabilized proteins in the presence of  dextran (68 kDa)have been examined.  This book will be very warmly welcomed by scholars  of regional science, biochemist, biophysics,  proteomics as well as biologist.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838326863\"\u003e\u003ch3\u003eFunction of alpha-crystallin in preventing amorphous and amyloid formation of proteins\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838326863","offer_id":39499070341213,"sku":"9783838326863","price":79.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/45418e7e-717b-41ce-9b35-884437a16cc1.jpg?v=1758875445","url":"https:\/\/shop.autorenwelt.de\/products\/the-chaperone-action-of-small-heat-shock-protein-alpha-crystallin-von-arezou-ghahghaei","provider":"Autorenwelt Shop","version":"1.0","type":"link"}