{"product_id":"the-application-of-gene-expression-profiling-to-clinical-breast-cancer-research-von-sherene-loi","title":"The application of gene expression profiling to clinical breast cancer research","description":"\u003cp\u003eThe book has three main results parts. Chapter 3  illustrates the first independent validation study of  a 70-gene signature developed from gene expression  profiling for use in breast cancer prognosis and  demonstration of its ability to add independent  prognostic information to the clinical prognostic  factors currently used. The successful validation of  this study preceded the design and implementation of  a world-wide randomized clinical trial evaluating the  gene signature's clinical utility. This trial has  commenced and is currently recruiting in Europe.  Chapter 4 describes the finding that  proliferation-related genes can predict clinical  outcome consistently in breast cancer and many gene  signatures developed for predicting breast cancer  prognosis derive a significant proportion of their  prognostic power from these genes. Finally, chapter 5  describes the use of proliferation-related genes to  define two distinct prognostic molecular subgroups  within estrogen receptor positive breast cancers.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838329734\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783838329734","offer_id":39447333568605,"sku":"9783838329734","price":79.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/57269f58-32c7-4089-a21a-6db5716e3b60.jpg?v=1776056463","url":"https:\/\/shop.autorenwelt.de\/products\/the-application-of-gene-expression-profiling-to-clinical-breast-cancer-research-von-sherene-loi","provider":"Autorenwelt Shop","version":"1.0","type":"link"}