{"product_id":"synthetic-transformations-of-conjugated-heterodienes-von-parvesh-singh","title":"Synthetic Transformations of Conjugated Heterodienes","description":"\u003cp\u003eThe present work entails the synthesis of different cross-conjugated (CC) heterodiene systems, and their transformations in various heterocyclic compounds using the hetero Diels-Alder (HDA) methodology. One of the main highlights of present work includes the development of simple and convenient procedure for the synthesis of stable CC azatrienes, and their tandem [2+2] cycloadditions and highly facile [3,3] sigmatropic Cope rearrangements with conjugated ketenes, leading to facile synthesis of various functionalized azocinone derivatives. A generalized and relevant study regarding the reactivity of thiazolic diazadienes with different ketenes was also conducted, and a remarkable increase in reactivity was observed with the introduction of electron donating group across the carbonyl group. Considering the biological and medicinal importance of C-5 or C-6 substituted pyrimidinones, the dienyl moiety of thiazolopyrimidinones was utilized further in Diels-Alder cycloadditions with both symmetrical and unsymmetrical dienophiles. Additionally, the synthesis of  various pyrans, thiopyrans, thiophenes, thiazoles, 1,3-thiazines etc. is also described.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783846592922\"\u003e\u003ch3\u003eHeterodiene cycloadditions\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783846592922","offer_id":39472656318557,"sku":"9783846592922","price":59.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/4e31181c-cae7-4841-bca2-10e50a0a6288.jpg?v=1756270774","url":"https:\/\/shop.autorenwelt.de\/products\/synthetic-transformations-of-conjugated-heterodienes-von-parvesh-singh","provider":"Autorenwelt Shop","version":"1.0","type":"link"}