{"product_id":"synthesis-of-tetrahydropyran-tetrahydrofuran-derivatives-von-boggu-jagan-mohan-reddy-n-prudhvi-raju","title":"Synthesis of Tetrahydropyran\/ tetrahydrofuran derivatives","description":"\u003cp\u003eIn this book, a metal-free protocol for the synthesis of 2, 3, 6-trisubstituted tetrahydropyrans using molecular iodine under mild conditions; Prins\/Ene cyclisation and Prins\/Ene bicyclization process for the stereoselective synthesis of a novel series of spiropyrolidine derivatives; a novel bicyclization strategy for the synthesis of indeno [2,1-c]pyran and cyclopenta[c]pyran scaffolds from aldehydes and exo-olefinic diols and a novel one-pot strategy has been developed for the synthesis of 3',4,4',5-tetrahydro-2H,2'H-spiro[furan-3,1'-naphthalen]-2'-one scaffolds through a pinacol 1,2-shift terminated Prins cyclization explained very efficiently. In contrast with the rapidly growing interest in such reactions, little effort has been focused on construction of O-containing heterocyclic scaffolds.These processes would be extremely useful for obtaining O- Heterocycles which comprises around 60% of all drug substances. Though few reports are there, still exploration in this field is highly desirable. These observations led us to choose Prins type cascade cyclizations as a key topic for our research.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786202095914\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9786202095914","offer_id":39465436610653,"sku":"9786202095914","price":49.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/01009c70-38a3-4292-b9e7-794fa12bb851.jpg?v=1765263229","url":"https:\/\/shop.autorenwelt.de\/products\/synthesis-of-tetrahydropyran-tetrahydrofuran-derivatives-von-boggu-jagan-mohan-reddy-n-prudhvi-raju","provider":"Autorenwelt Shop","version":"1.0","type":"link"}