{"product_id":"synthesis-of-novel-heterocycles-and-their-pharamacological-activity-novel-heterocycles-and-its-pharmacological-activity-von-dhananjay-mane-laxmikant-pavase","title":"Synthesis of Novel Heterocycles and Their Pharamacological Activity","description":"\u003cp\u003eAntibiotics are one of our most important weapons to cover bacterial infections and improve human life . Infectious diseases are the leaders among the challenging drug targets because of the multi-drug resist antimicrobial pathogens and continuous rise in the emerging infections from known and unknown sources. Tyrosine kinases are orally active, small molecules that have a favorable safety profile and can be easily combined with other forms of chemotherapy or radiation therapy. The combination of two pharmacophores into a single molecule is an effective and commonly used direction in modern medicinal chemistry for the exploration of novel and highly active compounds. A variety of safe and effective antiinflammatory agents are available, including aspirin and other nonsteroidal anti-inflammatories, with many more drugs under development. The pharmacophoric structural features of the selective COX-2 inhibitors possess a central heterocyclic five member ring system bearing two vicinal aryl moieties, such as pyrazole (celecoxib), 2(5H) furanone (rofecoxib), and isoxazole (valdecoxib).\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786139896486\"\u003e\u003ch3\u003eNovel Heterocycles and its Pharmacological activity\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9786139896486","offer_id":39433130606685,"sku":"9786139896486","price":76.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/cdaf505c-fb6f-4f99-ac7e-4c2984a3d022.jpg?v=1772868128","url":"https:\/\/shop.autorenwelt.de\/products\/synthesis-of-novel-heterocycles-and-their-pharamacological-activity-novel-heterocycles-and-its-pharmacological-activity-von-dhananjay-mane-laxmikant-pavase","provider":"Autorenwelt Shop","version":"1.0","type":"link"}