{"product_id":"synthesis-of-heterocyclic-compounds-with-expected-bioligical-activity-von-labeeb-mohamed-shaif","title":"Synthesis of Heterocyclic Compounds with expected Bioligical Activity","description":"\u003cp\u003eThis work has been carried out to investigate the chemical reactivity and synthetic  potentiality of 2-thioxohydropyridine 11a-d via their reaction with several active halogencontaining  compounds to afford the corresponding 2-alkylthiopyridine in some cases and  thieno[2,3-b]pyridine directly in most cases. Thieno[2,3-b]pyridine-2-carbohydrazides  obtained through the reaction of 2-ethoxycarbonylthienopyridines with hydrazine hydrate  which in turn, used to obtain the corresponding pyrimidinones 20-26(a-d), 1,3,4-  oxdiazoles 28, 30(a-d), pyrazolothienopyridine derivatives (32a-d) thienopyridine-3-  amines (34a-d), pyrazolones (36a-d), pyrazolidine-3,5-diones (38a-d). 3-  Aminopyrazolopyridine obtained via the reaction of 11a-e or 49a-e with hydrazine hydrate  which in turn, reacted with nitrous acid to give the diazonium salts 51a-e which coupled  with several active-hydrogen containing reagents to give the corresponding triazines. The  structures of all newly synthesized heterocyclic compounds were elucidated by  considering the data of IR, 1H NMR (¿ppm), mass spectra as well as that of elemental  analyses. Anti-Alzheimer, anti COX-2 and anti-Cancer activities were investigated for all  newly\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783847311881\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783847311881","offer_id":39476353269853,"sku":"9783847311881","price":79.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/2392ed29-2fbf-4ff4-a3df-6c76957c6c47.jpg?v=1768976561","url":"https:\/\/shop.autorenwelt.de\/products\/synthesis-of-heterocyclic-compounds-with-expected-bioligical-activity-von-labeeb-mohamed-shaif","provider":"Autorenwelt Shop","version":"1.0","type":"link"}