{"product_id":"synthesis-and-microbial-screening-of-some-glucopyranoside-derivatives-approach-to-pharmaceutical-uses-von-s-m-abe-kawsar","title":"SYNTHESIS AND MICROBIAL SCREENING OF SOME GLUCOPYRANOSIDE DERIVATIVES","description":"\u003cp\u003eMethyl ¿-D-glucopyranoside was easily prepared by the treatment of D-glucose with anhydrous methyl alcohol in the presence of hydrogen chloride at freezing temperature. Then N-acetylsulfanilylation of methyl ¿-D-glucopyranoside has been carried out by the direct method and afforded the 6-O-N-acetylsulfanilyl derivative in an excellent yield. In order to obtain newer products, the 6-O-N-acetylsulfanilyl derivative was further transformed into a series of 2,3,4-tri-O-acyl derivatives containing a wide variety of functionalities in a single molecular framework. The chemical structures of the newly synthesized compounds were elucidated by FTIR, Proton nuclear magnetic resonance spectroscopy, elemental and physicochemical properties analysis. All the newly synthesized D-glucose derivatives were tested for their in vitro antibacterial activity against some human pathogenic bacterial strains. The study revealed that a good number of compounds exhibited promising antibacterial activities. It is expected that the acylated derivatives of D-glucose may be considered as a potential source for developing new and better antibacterial agents against a number of pathogenic organisms.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786138938125\"\u003e\u003ch3\u003eApproach to Pharmaceutical Uses\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9786138938125","offer_id":39464305000541,"sku":"9786138938125","price":67.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/eb98a34c-d1f9-46bc-8145-ab99848189f9.jpg?v=1772950992","url":"https:\/\/shop.autorenwelt.de\/products\/synthesis-and-microbial-screening-of-some-glucopyranoside-derivatives-approach-to-pharmaceutical-uses-von-s-m-abe-kawsar","provider":"Autorenwelt Shop","version":"1.0","type":"link"}