{"product_id":"sulfonated-derivatives-of-2-4-xylidine-possible-therapeutic-agents-von-muhammad-athar-abbasi-sabahat-zahra-siddiqui","title":"Sulfonated Derivatives of 2,4-Xylidine: Possible Therapeutic Agents","description":"\u003cp\u003eSulfonamides are considered to be pharmaceutically important class of compounds. In the present work, N-(2,4-dimethylphenyl)-4-toluenesulfonamide was synthesized by the reaction of 2,4-dimethylaniline and 4-tosyl chloride (4-methylbenzenesulfonyl chloride) using 10% aqueous Na2CO3 solution as reaction medium. At the second step, the synthesized molecule was made to react with different alkyl\/aralkyl halides to yield the target compounds,using N,N-dimethylformamide (DMF) as reaction medium and lithium hydride as an activator. The synthesis of all the compounds was verified by spectral techniques using IR, 1H-NMR and EIMS; and further examined for their anti-enzymatic activities. The synthesized compounds represented the most potential against ¿-glucosidase and lipoxygenase enzymes.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659636585\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783659636585","offer_id":39449152258141,"sku":"9783659636585","price":39.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/c4493bc7-dc3c-4562-ad5c-642f79af68a0.jpg?v=1773469457","url":"https:\/\/shop.autorenwelt.de\/products\/sulfonated-derivatives-of-2-4-xylidine-possible-therapeutic-agents-von-muhammad-athar-abbasi-sabahat-zahra-siddiqui","provider":"Autorenwelt Shop","version":"1.0","type":"link"}