{"product_id":"sulfonamides-x-ray-structures-and-biological-studies-von-waqar-ahmad-asia-butt-und-islam-ullah-khan","title":"Sulfonamides: X-Ray Structures and Biological Studies","description":"\u003cp\u003eThe use of antibiotics in the treatment of various infections of humans caused by microbes has been a great success. Over the past years there has been an increase in the resistance of microorganisms against a large number of drugs. Keeping in view the biological activity and medicinal importance of sulfonamides, new sulfonamides are being synthesized. This book describes the synthesis of N-benzyl-4-methylbenzenesulfonamide, its N-alkylated derivatives and evaluation of their anti-microbial activity. N-benzyl-4- methylbenzene sulfonamide was synthesized by the condensation of benzyl amine with p-toluene benzenesulfonylchloride. The solvent used for this reaction was water.N-alkylated derivatives were prepared by reacting N-benzyl-4-methylbenzenesulfonamide with different alkylating agents and sodium hydride using DMF as solvent. The synthesized compounds were characterized by different techniques like X-ray crystallography, FT-IR, Elemental analyzer and melting point. Evaluation of anti-microbial activity was carried out by employing deep well method against different bacterial strains.The synthesized compounds exhibited appreciable anti-microbial activity.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659155314\"\u003e\u003ch3\u003eA new approach towards Biologically Active Compounds\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783659155314","offer_id":39487732940893,"sku":"9783659155314","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/9128301e-f558-4945-b9fd-9d360c62253e.jpg?v=1773469506","url":"https:\/\/shop.autorenwelt.de\/products\/sulfonamides-x-ray-structures-and-biological-studies-von-waqar-ahmad-asia-butt-und-islam-ullah-khan","provider":"Autorenwelt Shop","version":"1.0","type":"link"}