{"product_id":"studies-on-divergent-crp-dependent-promoters-von-mohamed-elrobh-und-stephen-j-w-busby","title":"Studies on divergent CRP-dependent promoters","description":"\u003cp\u003eBacterial genomes contain genes that are packed  closely together. For many genes, promoter regions  overlap, and regulatory segments that carry  divergent promoters are common. In this study, I  have focussed on promoters that are regulated by the  cyclic AMP receptor protein (CRP) of Escherichia  coli. CRP is a global regulator that directs the  activity of more than 100 genes, some of which are  oriented back-to-back, i.e., in a divergent fashion.  CRP is known to activate transcription initiation  through direct protein-protein contact with RNA  polymerase and CRP-dependent promoters are  classified into two classes, Class I and Class II,  according to the location of the CRP-binding site. I  have investigated whether a single bound CRP, either  at a Class I or a Class II location, can activate  divergent transcription.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838351971\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838351971","offer_id":39469198049373,"sku":"9783838351971","price":79.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/4bc8da4a-6065-4006-b291-5f1b92a1080c.jpg?v=1758087487","url":"https:\/\/shop.autorenwelt.de\/products\/studies-on-divergent-crp-dependent-promoters-von-mohamed-elrobh-und-stephen-j-w-busby","provider":"Autorenwelt Shop","version":"1.0","type":"link"}