{"product_id":"strychnos-spinosa-and-high-blood-pressure-von-yvanna-temasoa","title":"Strychnos spinosa and high blood pressure","description":"\u003cp\u003eThe aim of the present study is to valorize the use in traditional medicine of Strychnos spinosa (Loganiaceae) as an antihypertensive plant. On isolated rat aorta pre-contacted with phenilephrine the crude extract of the plant causes endothelium-dependent vasorelaxation with a relaxation EC50 value equal to 0.900 ± 0.054 mg\/ml. L-NAME inhibits the vasorelaxation effect induced by the extract of Strychnos spinosa with an increase in EC50 value of 2.254± 0.140mg\/ml, this shows that the vasorelaxation effect involves a mechanism that involves NO. The inhibition of the effect by propranolol, with an EC50 of 2.762±0.138mg\/ml demonstrates that the vasorelaxant effect involves the participation of ¿2 adrenergic receptors.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786204221991\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9786204221991","offer_id":39509062123613,"sku":"9786204221991","price":39.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/b1b1675e-4eef-4c7e-bf55-6cbbcfb8ca4a.jpg?v=1758954082","url":"https:\/\/shop.autorenwelt.de\/products\/strychnos-spinosa-and-high-blood-pressure-von-yvanna-temasoa","provider":"Autorenwelt Shop","version":"1.0","type":"link"}