{"product_id":"some-novel-1-4-thiazepine-derivatives-von-s-sarveswari","title":"Some novel 1, 4-thiazepine derivatives","description":"\u003cp\u003eThe 1, 4-thiazepine fused derivatives were synthesized by L-proline catalyzed one-pot mechanistic pathway. Though L-proline is being amphoteric molecule with both amine end carboxylic acid end, it worked as an enamine base for the catalysis. We aim to synthesize organic molecules with anti-cancer activity. This protocol provides a synthetic route for the efficient synthesis of 1, 4 -thiazepines. All the synthesized molecules were screened for the cytotoxicity studies. We have screened the synthesized 1, 4-thiazepines against to six cell lines, namely ¿Pancreas (PANC1), Renal (ACHN), Colon (HCT116), Non-small cell lung (H460), Lung (CALUl) and Normal breast epithelium (MCF10A)¿ with two concentration 1¿M and 10¿M concentration levels.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786205633953\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9786205633953","offer_id":40906177445981,"sku":"9786205633953","price":43.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/0ecde8dc-4fcd-48e0-ba5f-9974963d63e5.jpg?v=1773732240","url":"https:\/\/shop.autorenwelt.de\/products\/some-novel-1-4-thiazepine-derivatives-von-s-sarveswari","provider":"Autorenwelt Shop","version":"1.0","type":"link"}