{"product_id":"solvent-and-catalyst-free-organic-synthesis-von-subrahmanya-ishwar-bhat","title":"Solvent- and Catalyst-Free Organic Synthesis","description":"\u003cp\u003eThe toxicity and volatile nature of organic solvents that are widely used in huge amounts for chemical transformations have posed a serious threat to the environment. With the growing awareness in industry and academia for the sustainable development, the development of solvent-free reaction has received tremendous attention in recent years under the title ¿Green Chemistry¿. With this context, five different chemical transformations viz., aza-Michael addition of amines to ¿,¿-unsaturated acids, Knoevenagel condensation of salicylaldehydes and o-aminobenzaldehydes with malononitrile, cascade Knoevenagel-Michael reaction of 4-hydroxy-1-methylquinolin-2(1H)-one, aldehydes and several active methylene compounds, one-pot, three-component reactions for the synthesis of quinazolines and densely functionalized pyrroles have been studied under solvent- and catalyst-free conditions during the present investigation. From the results, it has been observed that, the organic transformations proceed faster and to a high degree of completion when the reaction occurred via homogeneous melt formation. However, the success of the reaction depends on the reactivity of the starting materials.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659834059\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783659834059","offer_id":39434717560925,"sku":"9783659834059","price":49.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/a0bcc8ec-231e-4c26-ab12-a8741016ea76.jpg?v=1773294850","url":"https:\/\/shop.autorenwelt.de\/products\/solvent-and-catalyst-free-organic-synthesis-von-subrahmanya-ishwar-bhat","provider":"Autorenwelt Shop","version":"1.0","type":"link"}