{"product_id":"solid-self-emulsifying-drug-delivery-system-of-glibenclamide-von-maria-saifee-sharda-zarekar-und-zahid-zaheer","title":"Solid Self Emulsifying Drug Delivery System of Glibenclamide","description":"\u003cp\u003eThe   study  was aimed  to  develop  solid  self  micro  emulsifying drug delivery system (S-SEDDS)  for dissolution enhancement of model drug Glibenclamide  using Aerosil 200 as solid carrier. SEDDS was prepared  using  oil,  surfactant  and  cosurfactant  respectively.  Pseudo  ternary  phase  diagram  was used to identify micro emulsion region for formulating stable SEEDS .Prepared  SEDDS  was  evaluated  for  turbidity  measurement, globule  size  and  zeta  potential,  viscosity  determination  and  %  transmittance. S-SEDDS was prepared by adsorption technique using Aerosil  200  as  solid  carrier.  Prepared  S-SEDDS  was  evaluated  for flow  properties,  drug  content,  FTIR,  SEM,  DSC  and  in-vitro dissolution  study.  Results  showed  that  prepared  liquid  SEDDS passed  all  evaluation  tests. S-SEDDS  showed  good  flow property and drug content. From the experiment, it is clear that even after conversion of the liquid SEDDS into the solid SEEDS, their is no significant alteration in its propertites.Thus Solid SEEDS can be used as a means of dissolution enhancement technique.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659540264\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783659540264","offer_id":39467430445149,"sku":"9783659540264","price":49.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/6565b4ef-ee59-4123-8793-e014685a73cd.jpg?v=1769492993","url":"https:\/\/shop.autorenwelt.de\/products\/solid-self-emulsifying-drug-delivery-system-of-glibenclamide-von-maria-saifee-sharda-zarekar-und-zahid-zaheer","provider":"Autorenwelt Shop","version":"1.0","type":"link"}