{"product_id":"small-interference-rna-sirna-mediated-gene-silencing-von-toyfiquz-zaman-md-rezanur-rahman-a-k-m-nazmul-huda","title":"Small Interference RNA (SiRNA) Mediated Gene Silencing","description":"\u003cp\u003eSmall interfering RNA (siRNA) is yet a developing field in molecular biology and has unfolded as a novel post transcription gene silencing strategy which has therapeutic potentiality. Indeed They have been shown to play a vital role in a wide range of biological process. They regulate the expression of a larege number of mRNAs. The gene silencing mediated by this small RNA (siRNA) a major component of gene regulation during various developmental and physiological processes. The accumulating knowledge about their biogenesis and gene silencing mechanism will add a new dimension to our understnding about the complex gene regulatory networks. Every gene in human genome to a some extent contributing to a disease is amenable to regulation with siRNA, therefore opening an unprecedented opportunities for drug discovery. Besides the well established role for siRNA as a tool for target screening and validation in vitro, recent progress of siRNA delivery in vivo raised expectations for siRNA drugs as the up-and-coming ¿magic bullet¿. Whether siRNA compounds will make it as novel chemical entities from ¿bench to bedside¿ will probably depend largely on improving their pharmaco kinetics in term\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786139854837\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9786139854837","offer_id":39464484536413,"sku":"9786139854837","price":35.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/c267e2f3-999d-45eb-88f1-3ca4fb73bb92.jpg?v=1757657035","url":"https:\/\/shop.autorenwelt.de\/products\/small-interference-rna-sirna-mediated-gene-silencing-von-toyfiquz-zaman-md-rezanur-rahman-a-k-m-nazmul-huda","provider":"Autorenwelt Shop","version":"1.0","type":"link"}