{"product_id":"silibinin-anti-tumor-effects-at-a-glance-von-mahdi-mashhadi-akbar-boojar","title":"Silibinin anti-tumor effects at a glance","description":"\u003cp\u003eSilibinin is a major component of silymarin (Silybum marianum), which has traditionally been used to treat a wide range of liver diseases. Recently, Silibinin and its derivatives in both in vitro and in vivo models have shown a significant inhibitory effect in different types of tumors including skin, breast, lung, colon, bladder, prostate, kidney and liver. The chemo-preventive potentials of this flavonoid are promoted by inducing apoptosis, enhancing tumor suppressor and cell cycle inhibitors, inhibiting growth factors, and attenuating proliferative mediators. In this paper, a summary of the important molecular mechanisms involved in Silibinin anti-cancer effects, animal studies and important clinical trials have been presented. The results of these studies will provide a more comprehensive perspective of Silibinin and help to optimize its effects in cancer chemotherapy.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786139471843\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9786139471843","offer_id":39455079039069,"sku":"9786139471843","price":39.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/fd7aba7d-629b-4835-8bb9-669cb25356fe.jpg?v=1769840560","url":"https:\/\/shop.autorenwelt.de\/products\/silibinin-anti-tumor-effects-at-a-glance-von-mahdi-mashhadi-akbar-boojar","provider":"Autorenwelt Shop","version":"1.0","type":"link"}