{"product_id":"signal-transduction-pathways-mechanisms-and-diseases-von-ari-sitaramayya-hrsg","title":"Signal Transduction: Pathways, Mechanisms and Diseases","description":"\u003cp\u003eAnotherareacoveredinthisbook,onenotoftenhighlightedinsignaltransd- tionbooks,isthatofsignalingplatforms,whichisemergingasasigni?cantareaof researchrelevanttocellularmetabolism,cellproliferation,differentiation,apop- sis,neurodegenerativediseases,andcancer. Theauthorscontributingtothisbook vii viii Preface areexpertsandactivecontributorstoresearchintheirspeci?careasofsignaling. I would like to thank them for their contributions and their suggestions in the developmentofthebook. IwouldliketoacknowledgethehelpofFrankTedeschi, astudentinmydepartment,whoassistedineditingthemanuscriptsandinprep- ingtheindex. IwouldalsoliketothankDr. SabineSchwarz,LifeSciencesEditorat SpringerVerlag,andDr. JuttaLindenbornwhohavebeenveryhelpfulatevery stageofproductionofthisbook. AriSitaramayya Contents PartI GProteinsandGProtein¿CoupledReceptors 1 TraditionalGPCRPharmacologyandBeyond. . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 AnnetteGilchristandMariaR. Mazzoni 2 RegulationofIntraneuronalTraf?ckingofG-Protein-Coupled ReceptorsbyNeurotransmittersInVivo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Ve¿roniqueBernard 3 SmallGTPasesandTheirRoleinRegulatingGProtein-Coupled ReceptorSignalTransduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 FabiolaM. RibeiroandStephenS. G. Ferguson 4 RegulationofGProteinReceptorCoupling,MoodDisorders andMechanismofActionofAntidepressants . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 MoranGolan,GabrielSchreiber,andSo?aAvissar 5 DysregulationofGProtein-CoupledReceptorSignaling inCancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 JoAnnTrejo PartII GrowthFactors 6 InsulinSignalinginNormalandDiabeticConditions . . . . . . . . . . . . . . . . . 101 PatriceEFort,HisanoriImai,RajuRajala,andThomasW. Gardner 7 EpidermalGrowthFactor(EGF)ReceptorSignaling andCancer . . . . .\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783642021114\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783662501917\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Hardcover - 9783642021114","offer_id":39530296475741,"sku":"9783642021114","price":213.99,"currency_code":"EUR","in_stock":true},{"title":"Softcover - 9783662501917","offer_id":39428409491549,"sku":"9783662501917","price":213.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/6a3acc38-04d2-4bcf-b1e0-d759647f90de.jpg?v=1780203045","url":"https:\/\/shop.autorenwelt.de\/products\/signal-transduction-pathways-mechanisms-and-diseases-von-ari-sitaramayya-hrsg","provider":"Autorenwelt Shop","version":"1.0","type":"link"}