{"product_id":"signal-transducing-molecules-and-colorectal-cancer-kashmir-scenario-von-aga-syed-sameer","title":"Signal Transducing Molecules and Colorectal Cancer - Kashmir Scenario","description":"\u003cp\u003eThe underlying theme of this doctoral thesis was  ¿ To evaluate the role of genetic aberrations  in different signal transducing molecules of  important signal transduction pathways that are  involved in the development and progression of CRC in  Kashmiri population. ¿ To assess the possible association between  the genetic aberrations of the signal transducing  molecules and various life style factors that are  likely to lead to the development and progression of  colorectal cancer. ¿ To observe the significance of multistep  model of CRC carcinogenesis in explaining the CRC  carcinogenesis in our Kashmiri population.  After assessing the various signal transducing  molecules for genetic aberrations we found that the  multi-step model of CRC carcinogenesis holds well in  explaining the CRC tumorigenesis in our Kashmiri  population but with a slight difference in manner and  frequency of genetic aberrations of key tumor  suppressor genes and oncogenes.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783843366564\"\u003e\u003ch3\u003eThe Genetic Alterations of the Signal Transducing Molecules and their role in the development and  progression of Colorectal Cancer in Kashmir Valley\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783843366564","offer_id":39470062469213,"sku":"9783843366564","price":79.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/97958ddb-7a38-435e-9e5f-35f05153d2d0.jpg?v=1757911768","url":"https:\/\/shop.autorenwelt.de\/products\/signal-transducing-molecules-and-colorectal-cancer-kashmir-scenario-von-aga-syed-sameer","provider":"Autorenwelt Shop","version":"1.0","type":"link"}