{"product_id":"role-of-tcf-in-body-axis-formation-von-miranda-molenaar","title":"Role of TCF in body axis formation","description":"\u003cp\u003eA novel role of TCF family in body axis formation.  Revolutionary high impact discoveries are described, elucidating the missing link in the Wnt pathway and protein-TCF combinations with dual functions.  By studying the primary axis formation of Xenopus  laevis, it was firstly shown that, in combination  with beta-catenin, TCF acts as a potent activator of  proto-oncogenes. Secondly, it was discovered that in  combination with the Groucho family of proteins, TCF  acts as suppressor of oncogene transcription.  Stronlgy suggesting that TCF controls oncogene  transcription in a dual fashion.  These discoveries contributed to the origination of a major area of cancer research and opened multiple angles for cancer therapy development.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838320526\"\u003e\u003ch3\u003eDiscovery of a Dual Action of XTCF-3 in Xenopus Body Axis Formation\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838320526","offer_id":39498899816541,"sku":"9783838320526","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/27143e84-db0b-4e3f-9434-5d3cc0b776a7.jpg?v=1758875229","url":"https:\/\/shop.autorenwelt.de\/products\/role-of-tcf-in-body-axis-formation-von-miranda-molenaar","provider":"Autorenwelt Shop","version":"1.0","type":"link"}