{"product_id":"review-of-current-extracorporeal-technologies-for-acute-liver-failure-von-chaitanya-bhanage","title":"Review of Current Extracorporeal Technologies for Acute Liver Failure","description":"\u003cp\u003eThe liver is the metabolic powerhouse of the body and  plays an important role in metabolism.The function of  the liver includes drug detoxification,plasma protein  synthesis and glycogen storage.Chronic liver failure  (CLF) takes months or years to develop, whereas acute  liver failure (ALF) may develop within 1-2 weeks.The  accepted treatment of end-stage CLF is  transplantation.However,the ability of the liver to  regenerate has pointed to the development of  temporary liver assist devices for the treatment of  ALF.Liver assist devices may be either cell-based,  involving liver cells cultured in a bioreactor, or  non-biological, involving passive transport across  synthetic membranes.Mixed results have been obtained  by both systems, with limited success in certain sub- groups of ALF.In the cell-based devices, the design  of the bioreactor must provide an architecture that  supports cell attachment, cell-cell interaction and  cell-matrix interaction for improvement in  function.Investigations on stem cells and growth of  liver-specific tissue constructs have recently been  reported and may point towards future developments in  liver assist devices.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838327389\"\u003e\u003ch3\u003eBiological \u0026amp; Non-Biological Liver Support Devices\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838327389","offer_id":39469183729757,"sku":"9783838327389","price":59.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/e056e9e2-dc72-44eb-918c-d241e83e268a.jpg?v=1769236357","url":"https:\/\/shop.autorenwelt.de\/products\/review-of-current-extracorporeal-technologies-for-acute-liver-failure-von-chaitanya-bhanage","provider":"Autorenwelt Shop","version":"1.0","type":"link"}