{"product_id":"resistance-to-molecular-therapies-for-hepatocellular-carcinoma-von-augusto-villanueva-hrsg","title":"Resistance to Molecular Therapies for Hepatocellular Carcinoma","description":"This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment; determines the role of the cancer stem cell phenotype in resistance; reviews the experimental models to study resistance; and addresses new approaches to overcome resistance to sorafenib, using successful examples from other malignancies.  \u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783319561967\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Hardcover - 9783319561967","offer_id":28578779136093,"sku":"9783319561967","price":160.49,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/73461_a036b8e1-4b78-4e12-ab93-b87c5865043f.jpg?v=1784261969","url":"https:\/\/shop.autorenwelt.de\/products\/resistance-to-molecular-therapies-for-hepatocellular-carcinoma-von-augusto-villanueva-hrsg","provider":"Autorenwelt Shop","version":"1.0","type":"link"}