{"product_id":"replicative-cessation-dna-damage-in-human-fibroblast-under-stress-von-sahar-khalil-gehad-hammouda-und-somaya-hosny","title":"Replicative Cessation \u0026 DNA Damage in Human Fibroblast under Stress","description":"\u003cp\u003eAging can be viewed partly as a degenerative process dictated by free radical reactions. Human diploid fibroblasts (HDFs) lose the capacity to proliferate and enter a state termed replicative senescence after a finite number of population doublings in vitro.  Presenescent human fibroblasts, when treated with a sub-lethal dose of H2O2, enter long term growth arrest resembling replicative senescence. H2O2 induced growth arrest; p53 protein expression and the effect of vitamin C as an antioxidant were determined in this study.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783846553268\"\u003e\u003ch3\u003eA study to investigate the replicative cessation, morphology and DNA damage in human fibroblasts under stress conditions\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783846553268","offer_id":39493624922205,"sku":"9783846553268","price":79.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/60132a41-7441-438d-b20e-398fea2a77bf.jpg?v=1769148248","url":"https:\/\/shop.autorenwelt.de\/products\/replicative-cessation-dna-damage-in-human-fibroblast-under-stress-von-sahar-khalil-gehad-hammouda-und-somaya-hosny","provider":"Autorenwelt Shop","version":"1.0","type":"link"}