{"product_id":"razrabotka-i-validaciya-mizoprostola-s-pomoshhju-uf-spektrofotometra-von-gandi-anusha","title":"RAZRABOTKA I VALIDACIYa MIZOPROSTOLA S POMOShh'Ju UF-SPEKTROFOTOMETRA","description":"\u003cp\u003eCel'ü nastoqschego issledowaniq qwlqlas' razrabotka i walidaciq stabil'nogo UF-spektroskopicheskogo metoda kolichestwennogo opredeleniq mizoprostola w nerasfasowannom wide, kotoryj shiroko ispol'zuetsq dlq lecheniq qzw, wyzwannyh NPVS. V issledowanii ispol'zowalas' tol'ko rasfasowannaq forma mizoprostola, a w kachestwe rastworitelq posle prowedeniq predwaritel'nyh testow na rastworimost' byla wybrana 0,1N HCl. Metodika byla razrabotana i walidirowana na dwuhluchewom spektrofotometre ELICO-Double beam SL-120\/UV. Ishodq iz fizicheskih parametrow i rastworimosti mizoprostola, byl prigotowlen standartnyj ishodnyj rastwor preparata i opredeleny maximumy pogloscheniq pri 281 nm. Linejnost' byla ustanowlena putem prigotowleniq rastworow w diapazone 2-10 mkg\/ml. Issledowanie prowodilos' w sootwetstwii s rekomendaciqmi Q3D, izlozhennymi w ICH. Razrabotannyj UF-spektroskopicheskij metod kolichestwennogo opredeleniq mizoprostola w sypuchih formah okazalsq bystrym, prostym, äkonomichnym i prigodnym dlq ego specificheskogo opredeleniq. Metod sootwetstwuet ustanowlennym trebowaniqm i demonstriruet horoshuü linejnost', a takzhe udowletworitel'nye pokazateli LOD, LOQ, tochnosti i precizionnosti.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786206504252\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9786206504252","offer_id":47144301691205,"sku":"9786206504252","price":19.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/dd47753c-a746-4d94-bd32-81aeef59222f.jpg?v=1750051875","url":"https:\/\/shop.autorenwelt.de\/products\/razrabotka-i-validaciya-mizoprostola-s-pomoshhju-uf-spektrofotometra-von-gandi-anusha","provider":"Autorenwelt Shop","version":"1.0","type":"link"}