{"product_id":"ras-family-gtpases-von-channing-der-hrsg","title":"RAS Family GTPases","description":"\n                \u003cp\u003eSince 1982, Ras proteins have been the subject of intense research investigation by the biomedical research community. The wide interest in Ras has been stimulated for three key reasons.\u003c\/p\u003e\n\u003cp\u003eFirst, their frequent mutational activation in human cancers establishes Ras proteins as important mediators of oncogenesis and targets for anti-cancer drug discovery. Second, Ras proteins act as signalling nodes activated by diverse extracellular stimuli, and activated Ras in turn regulates a diversity of cytoplasmic signalling networks. Third, Ras proteins are founding members of a large superfamily of Ras-related small GTPases. Over 150 Ras-related small GTPases are found in the human genome, with orthologs found in all vertebrate species and invertebrates.\u003c\/p\u003e\n\u003cp\u003eThis book features chapters by leading investigators in the field that highlight the current state-of-the art in Ras biochemistry, structure and biology. This book is an excellent reference for students in the biomedical sciences and for investigators in the field.\u003c\/p\u003e\n            \u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9781402043284\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9789048171101\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Hardcover - 9781402043284","offer_id":51074586502,"sku":"9781402043284","price":235.39,"currency_code":"EUR","in_stock":true},{"title":"Softcover - 9789048171101","offer_id":39416528797789,"sku":"9789048171101","price":219.98,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/b9a76ae3-dbea-4922-884c-4d9b33797cc9.jpg?v=1765870586","url":"https:\/\/shop.autorenwelt.de\/products\/ras-family-gtpases-von-channing-der-hrsg","provider":"Autorenwelt Shop","version":"1.0","type":"link"}